- Filtered by
- HydroxychloroquineHydroxychloroquine
NCT04362332
An Open Label Cluster Randomized Controlled Trial of Chloroquine, Hydroxychloroquine or Only Supportive Care in Patients AdmItted With Moderate to Severe COVID-19
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
- Population (9)
- Male and Female
- Hospitalization
- COVID-19
- NEWS2 Score
- Adult
- Aged (65+)
- Intervention (4)
- Chloroquine
- Supportive care
- Hydroxychloroquine
- Comparison (1)
- Support
- Outcome (5)
- Adverse Event
- Treatment discontinued
- Death
- NEWS2 Score
- Admission to Intensive Care Unit
NCT04858633
Efficacy of Hydroxychloroquine (HCQ) as Post Exposure Prophylaxis (PEP) for Prevention of COVID-19 in Asymptomatic Individual at Risk for SARS-CoV-2 Infection-A Randomized Control Clinical Trial
- Study Type
- Interventional
- Study Aim
- Prevention
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
NCT04355052
An Open-Label Study to Compare the Efficacy, Safety, and Tolerability of Hydroxychloroquine Combined With Azithromycin Compared to Hydroxychloroquine Combined With Camostat Mesylate and to no Treatment in Hospitalized Patients Suffering From a Mild or Moderate SARS CoV 2 Virus
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Single Arm/Controlled Before After
- Intervention Assignment
- Randomised
NCT04355026
Use of Bromhexine and Hydroxychloroquine for Treatment of COVID-19 Pneumonia
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
- Population (8)
- Male and Female
- Hospitalization
- COVID-19
- Adult
- Aged (65+)
- Intervention (2)
- Hydroxychloroquine
- Bromhexine
- Comparison (1)
- Hydroxychloroquine
- Outcome (6)
- Nosocomial Pneumonia
- Oxygen Supplementation
- Length of ICU Stay
- Mechanical ventilation
- Duration Of Hospital Stay
- Duration of Symptom
NCT04344379
Randomized Multicenter Study Evaluating the Efficacy of Azithromycin and Hydroxychloroquine in the Prevention of SARS-CoV-2 Infection in the Hospital Population Exposed to Virus
- Study Type
- Interventional
- Study Aim
- Prevention
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
NCT04354441
Randomized Trial Evaluating Effect of Outpatient Hydroxychloroquine on Reducing Hospital Admissions in Pregnant Women With SARS-CoV-2 Infection: HyPreC Trial
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
- Population (6)
- Female
- COVID-19
- Pregnant
- Adult
- Intervention (1)
- Hydroxychloroquine Sulfate
- Comparison (1)
- Placebo
- Outcome (16)
- Birth Weight
- Delivery mode
- Gestational Age
- Gender
- Miscarriage
- Adverse Event
- Jaundice
- Epidural Anesthesia
- Labour Induction
- Hospitalization
- Stillbirth
- Symptom severity
- Augmentation Of Labor
- Resuscitation
- Admission to Intensive Care Unit
- Cesarean Section
NCT04371406
Efficacy of Azithromycin-associated Hydroxychloroquine Therapy Given in General Practice in Early-stage Disease in COVID-19 Patients: Randomized Controlled Trial: MG-COVID
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
- Population (7)
- Male and Female
- COVID-19
- Adult
- Aged (65+)
- Intervention (4)
- Azithromycin
- Hydroxychloroquine
- General Practitioner
- Comparison (1)
- Placebo
- Outcome (14)
- Serious Adverse Event
- Death
- Withdrawn From Research Study
- Time to clinical recovery
- Adverse Event
- Viral load
- Clinical status
- Hospitalization
- Oxygen Saturation
- Mechanical ventilation
- Oxygen Therapy
- Admission to Intensive Care Unit
- Antibiotic Therapy
Eveleens 2021
Effect of hydroxychloroquine on the cardiac ventricular repolarization - a randomized clinical trial
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
Andy 2021
Smartphone electrocardiogram for QT interval monitoring in Coronavirus Disease 2019 (COVID-19) patients treated with Hydroxychloroquine
- Study Type
- Observational
- Study Aim
- Diagnostic/Prognostic
- Treatment and Management
- Study Design
- Case series/Case control/Cohort
- Intervention Assignment
- Not Applicable
Ip 2021
Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational study
- Study Type
- Observational
- Study Aim
- Treatment and Management
- Study Design
- Case series/Case control/Cohort
- Intervention Assignment
- Not Applicable
NCT04330144
A Study of Hydroxychloroquine as Post Exposure Prophylaxis for SARS-CoV-2(HOPE Trial)
- Study Type
- Interventional
- Study Aim
- Prevention
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
- Population (7)
- Male and Female
- Exposure to COVID-19
- Adult
- Aged (65+)
- Intervention (2)
- Hydroxychloroquine
- Prophylaxis
- Comparison (1)
- Usual Care
- Outcome (1)
- COVID-19
NCT04423991
Identification of a Responsive Subpopulation to Hydroxychloroquine in COVID-19 Patients Using Machine Learning: the IDENTIFY Trial
- Study Type
- Observational
- Study Aim
- Diagnostic/Prognostic
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Not Applicable
IRCT20200428047228N2
Hydroxychloroquine in comparison with hydroxychloroquine + azithromycin in patients with covid-19
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
- Population (9)
- Male and Female
- Hospitalization
- COVID-19
- Adult
- Aged (65+)
- Child
- Intervention (2)
- Azithromycin
- Hydroxychloroquine
- Comparison (2)
- Hydroxychloroquine
- Placebo
- Outcome (10)
- Blood Count
- Death In Hospital
- Fever
- Length of ICU Stay
- C-reactive Protein
- Oxygen Saturation
- Dyspnea
- Computerised Tomography
- Adverse Drug Reaction
- Duration Of Hospital Stay
NCT04370782
A Randomized Study Evaluating the Safety and Efficacy of Hydroxychloroquine and Zinc in Combination With Either Azithromycin or Doxycycline for the Treatment of COVID-19 in the Outpatient Setting
- Study Type
- Interventional
- Study Aim
- Treatment and Management
- Study Design
- Parallel/Crossover
- Intervention Assignment
- Randomised
- Population (9)
- Male and Female
- Co-morbid conditions
- COVID-19
- Adult
- Aged (65+)
- Intervention (6)
- Zinc
- Hydroxychloroquine
- Doxycycline
- Azithromycin
- Comparison (0)
- Outcome (8)
- Length of ICU Stay
- Hospitalization
- Adverse Drug Reaction
- Prolonged QT Interval
- Symptom severity
- Emergency Department Patient Visit
- Mechanical ventilation
- Duration of Symptom
Meriglier 2020
Safety of hydroxychloroquine and darunavir or lopinavir in COVID-19 infection
- Study Type
- Observational
- Study Aim
- Treatment and Management
- Study Design
- Case series/Case control/Cohort
- Intervention Assignment
- Not Applicable
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