NCT04345861
Randomized Trial Assessing Efficacy and Safety of Hydroxychloroquine Plus Azithromycin Versus Hydroxychloroquine for Hospitalized Adults With COVID-19 Pneumonia
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (9)
  2. Male and Female
  3. Hospitalization
  4. COVID-19
  5. Pneumonia associated with COVID-19
  6. Adult
  7. Aged (65+)
  1. Intervention (4)
  2. Hydroxychloroquine
  3. Azithromycin
  4. Placebo
  1. Comparison (0)
  1. Outcome (10)
  2. Time to clinical improvement
  3. Electrocardiogram
  4. Clinical status
  5. Death
  6. Adverse Event
  7. Admission to Intensive Care Unit
  8. Mechanical ventilation
  9. Chest CT
  10. Duration Of Hospital Stay
  11. Ordinal Scale
References (1)
Mercuro 2020
Risk of QT Interval Prolongation Associated With Use of Hydroxychloroquine With or Without Concomitant Azithromycin Among Hospitalized Patients Testing Positive for Coronavirus Disease 2019 (COVID-19)
  1. Study Type
  2. Observational
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Case series/Case control/Cohort
  1. Intervention Assignment
  2. Not Applicable
References (1)
IRCT20200428047228N2
Hydroxychloroquine in comparison with hydroxychloroquine + azithromycin in patients with covid-19
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (9)
  2. Male and Female
  3. Hospitalization
  4. COVID-19
  5. Adult
  6. Aged (65+)
  7. Child
  1. Intervention (2)
  2. Azithromycin
  3. Hydroxychloroquine
  1. Comparison (2)
  2. Hydroxychloroquine
  3. Placebo
  1. Outcome (10)
  2. Blood Count
  3. Death In Hospital
  4. Fever
  5. Length of ICU Stay
  6. C-reactive Protein
  7. Oxygen Saturation
  8. Dyspnea
  9. Computerised Tomography
  10. Adverse Drug Reaction
  11. Duration Of Hospital Stay
References (1)
NCT04318015
Chemoprophylaxis With Hydroxychloroquine in Healthcare Personnel in Contact With COVID-19 Patients: A Randomized Controlled Trial (PHYDRA Trial)
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  3. Prevention
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (8)
  2. Male and Female
  3. Healthcare Professional
  4. Exposure to COVID-19
  5. Adult
  6. Aged (65+)
  1. Intervention (1)
  2. Hydroxychloroquine
  1. Comparison (1)
  2. Placebo
  1. Outcome (4)
  2. Absenteeism
  3. COVID-19
  4. Viral Disease
  5. Severe COVID-19
References (1)
NCT04355026
Use of Bromhexine and Hydroxychloroquine for Treatment of COVID-19 Pneumonia
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (8)
  2. Male and Female
  3. Hospitalization
  4. COVID-19
  5. Adult
  6. Aged (65+)
  1. Intervention (2)
  2. Hydroxychloroquine
  3. Bromhexine
  1. Comparison (1)
  2. Hydroxychloroquine
  1. Outcome (6)
  2. Nosocomial Pneumonia
  3. Oxygen Supplementation
  4. Length of ICU Stay
  5. Mechanical ventilation
  6. Duration Of Hospital Stay
  7. Duration of Symptom
References (1)
NCT04315896
Hydroxychloroquine Treatment for Severe COVID-19 Respiratory Disease: Randomised Clinical Trial (HYDRA Trial)
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (7)
  2. Male and Female
  3. Severe COVID-19
  4. Adult
  5. Aged (65+)
  1. Intervention (2)
  2. Hydroxychloroquine
  3. Oral
  1. Comparison (2)
  2. Placebo
  3. Oral
  1. Outcome (4)
  2. Adverse Event
  3. All Cause Mortality
  4. Mechanical ventilation
  5. Duration Of Hospital Stay
References (1)
References (1)
NCT04333654
A Phase 1b, Randomized, Double-blinded, Placebo-controlled Study of Hydroxychloroquine in Outpatient Adults With COVID-19
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (7)
  2. Male and Female
  3. COVID-19
  4. Adult
  5. Aged (65+)
  1. Intervention (0)
  1. Comparison (0)
  1. Outcome (0)
References (1)
IRCT20190122042450N4 // U07
The effect of hydroxychloroquine to prevent coronavirus disease
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  3. Health Services Research
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (5)
  2. Male and Female
  3. COVID-19
  4. Adult
  1. Intervention (2)
  2. Hydroxychloroquine
  3. Preventive
  1. Comparison (1)
  2. Quarantine
  1. Outcome (3)
  2. Respiratory Symptom
  3. Clinical status
  4. Viral load
References (1)
Ahn 2020a
A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
  1. Study Type
  2. Observational
  1. Study Aim
  2. Diagnostic/Prognostic
  1. Study Design
  2. Case Report
  1. Intervention Assignment
  2. Not Applicable
References (1)
Rosenberg 2020a
Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State
  1. Study Type
  2. Observational
  1. Study Aim
  2. Diagnostic/Prognostic
  3. Treatment and Management
  1. Study Design
  2. Case series/Case control/Cohort
  1. Intervention Assignment
  2. Not Applicable
References (1)
NCT04351620
High-dose Hydroxychloroquine for the Treatment of Ambulatory Patients With Mild COVID-19
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Single Arm/Controlled Before After
  1. Intervention Assignment
  2. Non-randomised
References (1)
EUCTR2020-001331-26-GB
Preventative Drug Treatment for COVID-19 Infectious Disease
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Prevention
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (7)
  2. Male and Female
  3. Healthcare Professional
  4. COVID-19
  5. Adult
  6. Aged (65+)
  1. Intervention (1)
  2. Drug Therapy
  1. Comparison (1)
  2. Placebo
  1. Outcome (0)
References (3)
IRCT20150808023559N20 // U07
Efficacy of hydroxychloroquine plus favipiravir drug regimen in comparison with hydroxychloroquine plus kaletra in hospitalized patients with COVID-19
  1. Study Type
  2. Interventional
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Parallel/Crossover
  1. Intervention Assignment
  2. Randomised
  1. Population (7)
  2. Male and Female
  3. COVID-19
  4. Adult
  5. Aged (65+)
  1. Intervention (2)
  2. Favipiravir
  3. Hydroxychloroquine
  1. Comparison (2)
  2. Lopinavir And Ritonavir
  3. Hydroxychloroquine
  1. Outcome (2)
  2. Death
  3. Duration Of Hospital Stay
References (1)
0 Selected
ExportClear