Cochrane COVID-19 Study Register
Abadías-Granado 2020

Generalized Pustular Figurate Erythema. First Report in Two COVID-19 Patients on Hydroxychloroquine

  1. Study Type
  2. Observational
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Case Report
  1. Intervention Assignment
  2. Not Applicable

Generalized Pustular Figurate Erythema. First Report in Two COVID-19 Patients on Hydroxychloroquine

Abadias-Granado I, Palma-Ruiz AM, Cerro PA, Morales-Callaghan AM, Gomez-Mateo MC, Gilaberte Y, Schwartz RA
Journal article
Report Results
Generalized pustular figurate erythema (GPFE) is a distinctive severe cutaneous drug reaction with widespread urticarial or edematous plaques scattered over the entire body that become topped with non-follicular pustules that evolve into erythematous and sometimes atypical targetoid plaques converging into annular and arcuate patterns prominent on the trunk and extremities (1). It has been linked with medications, especially hydroxychloroquine. We describe two COVID-19 patients on hydroxychloroquine who developed this eruption 2 and 3 weeks after the onset of hydroxychloroquine. This report is the first to our knowledge of COVID-19 patients on hydroxychloroquine developing GPFE