Cochrane COVID-19 Study Register
Compés 2020

Nutritional treatment in critically ill patients with COVID-19 disease: spanish experience in a nniversity hospital (Extended)

  1. Study Type
  2. Observational
  1. Study Aim
  2. Not applicable
  1. Study Design
  2. Case series/Case control/Cohort
  1. Intervention Assignment
  2. Not Applicable

Nutritional treatment in critically ill patients with COVID-19 disease: spanish experience in a nniversity hospital (Extended)

Compes CC, Gimeno CV, Miguelez M, Carrascal M, Romero R, Carrasco P, Serrano C, Breton I, Motilla M, Arhip L, Morales A, Rubio S, Calvo C, Wong J, Camblor M
Rationale: Patients with COVID-19 disease develop respiratory insufficiency, 5% of which needs ICU treatment. Describe the experience of a tertiary hospital in the nutrition treatment during this pandemic. Methods: Retrospective study including COVID-19 patients from 5 ICU units of our hospital that needed medical nutrition treatment (MNT). Collected variables: sex, age, BMI, underlying diseases, time from hospitalisation to ICU admission, type of respiratory support, caloric and protein requirements (25 kcal/kg adjusted body weight(ABW), 1.3 g/kg ABW/day), MNT type (enteral nutrition (EN), parenteral nutrition (PN), mixed EN+PN), total calories (including propofol) and proteins administered, percentage of caloric and protein goal in ICU day 4th and 7th, metabolic complications, kidney failure, mortality. Results: 139patients were included (74.8% men), 59.6±13.8 years, BMI 29.9±5.3 kg/m2. Comorbidities: 52.3% overweight, 38.6% obesity, 47.5% hypertension, 43.9% dyslipidaemia, 18.7% diabetes. 82.7% required mechanical ventilation (90.4% of whom pronation), 3.6% ECMO. Hospitalisation to ICU admission time: 3.3±4.3 days. 12.2% EN, 29.5% PN, 51.8% mixed EN+PN. Caloric and protein requirements: 1773±252 kcal and 91.7±17 g. Table 1 presents total calories and proteins administered at day 4th and 7th. 61.9% and 8.6% patients had low levels of P and Mg in the first week, 74.1% hyperglycaemia, 7.9% hypoglycaemia, 70.5% hypertriglyceridemia (23.5% >500 mg/dl), 25.9% AKF and 10.8% KRT, 31.7% mortality. 5 patients are still in ICU. ICU length of stay was 21.8±15.7 days. [Formula presented] Conclusion: Most of our patients reached estimated caloric and protein target at day 4th and 7th of ICU. PN was necessary in most of our sample in the first week to reach nutritional requirements. We observed a high rate of metabolic complications which requires close monitoring of nutritional treatment. References: Clinical Nutrition 38 (2019) 48-79 Disclosure of Interest: None declared