Cochrane COVID-19 Study Register
Mazucatto 2020a

Mortality due to covid1-19 x protein supply. Is there a relationship?

  1. Study Type
  2. Observational
  1. Study Aim
  2. Diagnostic/Prognostic
  3. Mechanism
  4. Not applicable
  1. Study Design
  2. Cross-sectional
  1. Intervention Assignment
  2. Not Applicable

Mortality due to covid1-19 x protein supply. Is there a relationship?

Mazucatto IH, Totti F, Longhi S, Alves FR, Lins L, Bailer M, Balula A
Rationale: To evaluate whether there is a relationship between increased mortality from COVID 19, relate the offer of protection during the period in which he received enteral nutritional therapy. Methods: Retrospective, observational study, with analysis of 16 deaths by COVID-19, which occurred between the months of March and April / 2020, of patients admitted to an ICU of a particular hospital in the city of Sao Paulo, Brazil. For inclusion criteria were adopted: adult patients, admitted to the ICU and who received enteral nutritional therapy for more than 72 hours. For calculations of nutritional offer, the ESPEN Guidelines for critical patients were used, considering the adequate offer or the minimum average value of 80%. The data were analyzed using Excel planning and statistically defined. Results: Of the 16 patients who died, 13 (81%) received enteral nutritional therapy (TNE) and, of these, 9 (69%) for a period longer than 72 hours, with the average age of those 71.6 years (σ 7, 12) and the average offer period for TNE was 13 days (σ 7.81). The average protein supply was 67.9% / day (σ 18.6) and only 2 patients (22.2%) received less than 80% of the protein target used. There was a weak correlation (r 0.379) between the days of diet and protein supply. There was a medium correlation (r 0.5250) between age and protein supply. Conclusion: Given the data, it is possible to conclude that an inadequate protein supply has contributed to the mortality of this group of patients, since only 2 patients (22.2%) receive less than 80% of the goal achieved, this is the first time tested in scientific studies is essential for the recovery of patients in the ICU. References: Barazzoni R et al., ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection, Clinical Nutrition, https://doi.org/10.1016/j.clnu.2020.03.022 Disclosure of Interest: None declared