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Cochrane COVID-19 Study Register
Study record
ChiCTR2100044867First Published: 2022 Jan 28Updated Date: 2022 Jan 28

Influence of different atomized drugs and their duration on bacterial filter resistance

  1. Study Type
  2. Other
  1. Study Aim
  2. Treatment and Management
  1. Study Design
  2. Case series/Case control/Cohort
  1. Intervention Assignment
  2. Not Applicable
Reference record

Influence of different atomized drugs and their duration on bacterial filter resistance

ChiCTR2100044867
Trial registry record
No Results
INTERVENTION: No atomization group: Bacterial filters are placed in the respiratory circuit; Compound ipratropium bromide solution atomization group: Bacterial filters were placed in the respiratory circuit and atomized with Compound ipratropium bromide solution; Amphotericin B atomization group:Bacterial filters were placed in the respiratory circuit and atomized with amphotericin B;Interferon atomization group:Bacterial filters were placed in the respiratory circuit and atomized with interferon; CONDITION: Severe Novel Coronavirus Pneumonia (COVID-19), COPD, ARDS PRIMARY OUTCOME: Bacterial filter resistance; SECONDARY OUTCOME: Pressure before filtering; Post-filtration pressure; Gas flow rate; INCLUSION CRITERIA: 1. Dec.1, 2020 solstice Admitted to intensive care unit of the First Affiliated Hospital of Guangzhou Medical University on Jan. 1, 2021. 2. The duration of mechanical ventilation was > 72 hours. 3. Use bacterial filters in the breathing loop. 4. During mechanical ventilation, they were atomized with amphotericin B, cobivent or interferon. 5.Subjects voluntarily participate in this study and sign the informed consent