Reference record
COVID-19 Breakthrough Infection in Fully Vaccinated People and in People Who Received a Booster Dose
NCT05392075
First Published (first received 2022 May 26)https://clinicaltrials.gov/show/NCT05392075 (https://clinicaltrials.gov/show/NCT05392075)
Trial registry recordNo Results
A novel coronavirus, SARS-CoV-2 (formerly known as the 2019 novel coronavirus [2019-nCoV])
was identified as the agent that caused an outbreak of pneumonia (termed COVID-19) in Wuhan,
China in December 2019. The virus quickly spread to other countries and on March 11, 2020,
the World Health Organization (WHO) declared COVID-19 a pandemic. By March 2021, many nations
and organizations embarked on finding a cure or vaccine for this devastating viral infection.
The Pfizer COVID-19 mRNA vaccine was the first to obtain emergency use authorization (EUA)
from the Food & Drug Administration (FDA) on December 11, 2020, followed by the Moderna
COVID-19 mRNA vaccine on December 18, 2020, and the Janssen COVID-19 viral vector vaccine on
February 27, 2021. The mRNA vaccines and the viral vector vaccine are designed based on the
spike protein of SARS-COV-2. These vaccines had been administered to millions of Americans
prior to July 2021