Reference record
Pathophysiology of Gas Exchange and Time Course Changes in Spontaneously Breathing Patients With Acute Respiratory Failure Due to COVID-19. A Multicenter Prospective Study
NCT05392062
First Published (first received 2022 May 26)https://clinicaltrials.gov/show/NCT05392062 (https://clinicaltrials.gov/show/NCT05392062)
Trial registry recordNo Results
The pathophysiology of SARS-COV-2 related respiratory disease is still poorly understood,
especially in its most severe form called acute respiratory distress syndrome (ARDS). In this
case, very few studies have investigated changes in gas exchange during COVID-19 progression
in spontaneously breathing patients. The investigators purpose in this study to explore the
pathophysiology of gas exchange and time course changes in spontaneously breathing patients
with acute respiratory failure due to COVID-19. Moreover, our aim is to identify early
markers associated with worsening respiratory failure and requiring endotracheal intubation