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Cochrane COVID-19 Study Register
Study record
Mohamed 2022vFirst Published: 2022 Nov 23Updated Date: 2022 Nov 23

Acute motor axonal neuropathy following SARS-CoV-2 infection in the third trimester of pregnancy

  1. Study Type
  2. Observational
  1. Study Aim
  2. Diagnostic/Prognostic
  3. Treatment and Management
  1. Study Design
  2. Case Report
  1. Intervention Assignment
  2. Not Applicable
Reference record

Acute motor axonal neuropathy following SARS-CoV-2 infection in the third trimester of pregnancy

Mohamed MMG, Jadhav A, Banuelos P, Lacasse A, Kumar V
Journal article
Report Results
Neurological complications following SARS-CoV-2 infections are increasingly recognized. Despite that, sequelae from SARS-CoV-2 infection in gravid women are uncommonly reported. We present a case of acute motor axonal neuropathy, a variant of Guillain-Barre syndrome, in a 26-year-old primigravida at 34 weeks' gestation. She presented with worsening diplopia, dysphagia, and lower extremity sensory and motor deficits after testing positive for SARS-CoV-2 2 weeks earlier. Due to rapidly progressive symptoms, she required endotracheal intubation and mechanical ventilation. Initially she was diagnosed with Miller Fisher syndrome, but serology and electromyography studies were consistent with acute motor axonal neuropathy. Spontaneous preterm delivery, supportive care, and intravenous immunoglobulin therapy resulted in clinical improvement. Steady recovery was achieved by a prolonged rehabilitation program